Miconia kellyana is described as a new species that is known only from a limited area of montane tropical forest in Cusuco National Park in northwestern Honduras. Line drawings, field photographs, a distribution map, a recommended conservation assessment, and a discussion of morphologically similar species are provided. This species can be recognized by its 5-plinerved leaves with secondary veins diverging from the midvein above the blade base, cauline internode indumentum consisting of simple spreading trichomes, stalked-stellate trichomes, and apically bifid trichomes 0.5–1 mm long, conspicuous external calyx teeth that exceed the calyx lobes in length and largely conceal them, hypanthia with yellowish mostly simple trichomes sparingly intermixed with apically bifid and stalked-stellate trichomes 1–1.5 mm long that completely conceal the surface at anthesis, and isometric and isomorphic stamens with a connective that is prolonged ventro-basally above the filament insertion into a bilobulate ventral appendage less than 0.25 mm long. The new species is compared with M. chinantlana, M. globulifera, and M. tixixensis. All of these related species occur only in adjacent areas of neighboring Guatemala and/or a few southern states of Mexico.